Navigating controversies in stage III NSCLC: a multidisciplinary case discussion on evolving treatment paradigms.
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Authors
Horne, Ashley
Gomez-Randulfe, Igor
Ford, Amy
Milton, Richard
Jankowska, Petra
O'Dowd, Emma
Greystoke, Alastair
Faivre-Finn, Corinne
Issue Date
2026-04-15
Type
Journal Article
Review
Review
Language
en
Keywords
Lung Cancer , Pneumonectomy , Radiotherapy , Surgery , Systemic therapy , Tumour board
Alternative Title
Abstract
The management of stage III non-small cell lung cancer (NSCLC) has become increasingly complex, driven by advances in neoadjuvant and perioperative chemo-immunotherapy as well as targeted therapies. These evolving treatment paradigms have introduced new challenges for multidisciplinary teams (MDTs), regarding patient selection, treatment sequencing, surgical planning and definitions of operability and resectability.
Description
© 2026 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license ( http://creativecommons.org/licenses/by/4.0/ ).
Citation
Publisher
License
Copyright © 2026. Published by Elsevier B.V.
Journal
Lung cancer (Amsterdam, Netherlands)
Volume
216
Issue
PubMed ID
ISSN
1872-8332