Pharmacogenomics to optimise psychotropic prescribing: a survey of mental health professionals' perceptions, knowledge, and educational needs.
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Authors
Panconesi, Daniele
Murtough, Stephen
Cotic, Marius
Khani, Noushin Saadullah
Varney, Lauren
Richards-Brown, Maria
Abidoph, Rosemary
Mills, Daisy
Richards-Belle, Alvin
Molai, Jazmin
Issue Date
2026-01-20
Type
Journal Article
Language
en
Keywords
Alternative Title
Abstract
A survey was conducted to determine attitudes, knowledge, and educational needs of mental health professionals regarding pharmacogenomics. We recruited 128 clinicians working in mental health in England, and we assessed their experiences using an adapted version of the "U-PGx Clinician's Questionnaire". Responding clinicians had positive attitudes towards pharmacogenomics testing, although they lacked confidence in ordering and interpreting tests, for which most had never received any formal training. Only 6% of clinicians answered all 4 knowledge testing questions correctly, and barriers to clinical implementation included lack of familiarity and knowledge for several pharmacogenomics concepts, such as drug metabolism and genetics, as well as needing support from their working institution. Looking ahead, we found that accredited workshops and patient cases were preferred learning formats, and we suggest tailored education programmes to enable mental health professionals to apply pharmacogenomics in clinical practice.
Description
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Citation
Panconesi, D. et al. (2026) 'Pharmacogenomics to optimise psychotropic prescribing: a survey of mental health professionals’ perceptions, knowledge, and educational needs', The Pharmacogenomics Journal 26(1) 2. Available At: https://doi.org/10.1038/s41397-025-00394-x
Publisher
Springer Nature
License
© 2026. The Author(s).
Journal
The pharmacogenomics journal
Volume
26
Issue
1
PubMed ID
ISSN
1473-1150