The role of Mediterranean and MIND diets in stroke incidence, severity, and recovery
No Thumbnail Available
Authors
Aderinto, Nicholas
Abraham, Israel Charles
Olatunji, Gbolahan
Kokori, Emmanuel
Gaur, Aditya
Yusuf, Ismaila Ajayi
Ogunsola, Oluwatomisin Priscilla
Ukpong, Bieteti Sebastian
Ibiyemi, Oluwaseun Ibitoye
Babalola, Adetola Emmanuel
Issue Date
2025-05-29
Type
Article
Language
en
Keywords
Alternative Title
Abstract
Stroke is a leading global health challenge, contributing to mortality, disability, and cognitive decline. Modifiable risk factors, notably poor diet, drive its rising incidence. This review assesses the impact of adherence to the Mediterranean (MedDiet) and MIND diets on stroke incidence, severity, recovery, and prognosis. We searched PubMed, Embase, Scopus, and other databases (inception to December 2024) for studies involving adults (≥ 18 years) with stroke, comparing MedDiet or MIND diet to standard/no interventions. Primary outcomes included stroke incidence, severity (as measured by NIHSS), and recovery (as assessed by mRS); secondary outcomes comprised cognitive function (evaluated by MoCA and MMSE) and biomarkers (inflammation and neurodegeneration). Twenty-four studies (including RCTs, cohort, case–control, and cross-sectional designs) were analyzed. Higher adherence to the MedDiet reduced the risk of ischemic stroke by 21–30% (HR: 0.70–0.79, 95% CI: 0.53–0.92, p < 0.01), lowered severity (β = -1.84, 95% CI: -3.15 to -0.52, p = 0.006), and improved recovery (OR: 1.68, 95% CI: 1.21–2.34, p = 0.002). The MIND diet slowed cognitive decline (β = 0.119, 95% CI: 0.039–0.199, p = 0.004) and reduced mortality (HR: 0.68, 95% CI: 0.54–0.85, p = 0.002). Olive oil, nuts, and leafy greens were key contributors to the diet. Younger age and lower education predicted poor adherence. These diets show promise for stroke prevention and rehabilitation; however, further studies are needed to elucidate the mechanisms and optimize long-term strategies.
Description
Citation
Aderinto, N. et al. (2025) 'The role of Mediterranean and MIND diets in stroke incidence, severity, and recovery', Nutrire 50(40). Available At: https://doi.org/10.1186/s41110-025-00347-1
Publisher
Springer Nature
License
Journal
Volume
Issue
PubMed ID
ISSN
2316-7874