Rare but There: Ceftriaxone-Induced Neutropenia in a Patient With a Brain Abscess.
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Authors
Naseem, Muhammad
Maheen
Ullah, Safi
Alizai, Qaidar
Motie, Ali
Issue Date
2024-06-28
Type
Case Reports
Journal Article
Journal Article
Language
en
Keywords
ceftriaxone-induced neutropenia , cerebral abscess , drug induced neutropenia , gcsf role in treatment of neutropenia , reversible neutropenia
Alternative Title
Abstract
This case report details the case of a 70-year-old man with Marfan syndrome and hypertension who developed neutropenia after an eight-week course of ceftriaxone, used to treat a brain abscess. Initially presenting with tonic-clonic seizures and headaches, his condition was managed with ceftriaxone and metronidazole. The subsequent drop in neutrophil counts from 7.54 × 10^9/L to 0.87 × 10^9/L leads to the discontinuation of ceftriaxone and the administration of granulocyte-colony stimulating factor (G-CSF), which effectively restored the neutrophil levels. This case highlights that clinicians should be aware of ceftriaxone-induced neutropenia as a potential complication, especially in patients undergoing prolonged therapy. Regular monitoring and timely management are essential for patient safety and favorable outcomes.
Description
© Copyright 2024
Naseem et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Citation
Naseem, M.; Maheen.; Ullah, S.; Alizai, Q. and Motie, A. (2024) 'Rare but There: Ceftriaxone-Induced Neutropenia in a Patient With a Brain Abscess', Cureus, 16(6) e63411. Available at: https://doi.org/10.7759/cureus.63411
Publisher
Springer Nature
License
Copyright © 2024, Naseem et al.
Journal
Cureus
Volume
16
Issue
6
PubMed ID
ISSN
2168-8184